产品货号：
Z33043
中文名称：
AKT2 FITC抗体
英文名称：
Anti-AKT2 FITC Antibody (Clone#16G11.E8)
产品规格：
50μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AKT2 FITC Antibody (Clone#16G11.E8) |
| 指标别名 | AKT2;PKB beta;PKBB;PKBBETA;PRKBB;Protein kinase Akt 2;Protein kinase B beta;RAC BETA;RAC PK beta |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IF,IHC,WB |
| 基因名称 | AKT2 |
| 克隆号 | 16G11.E8 |
| 抗体来源 | Rat |
| 免疫原 | Anti-AKT2 Antibody was produced in rat by repeated immunizations with a synthetic peptide corresponding to internal residues of human AKT2 protein. |
| 成分 | 0.02M Potassium Phosphate,0.5M Sodium Chloride,pH7.2,10mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free,0.01% (w/v) Sodium Azide |
| 纯化方式 | Anti-AKT2 antibody is directed against human AKT2.The antibody detects both unphosphorylated and phosphorylated forms of the protein.Anti-AKT2 was purified from concentrated tissue culture supernate by Protein G chromatography.Cross-reactivity with AKT2 from other species has not been determined,however,the sequence of the immunogen shows 88% identity to mouse and 90% identity with rat,therefore,cross-reactivity is expected. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | Lyophilized |
| 保存条件 | Store vial at 4℃ prior to restoration.Restore with deionized water (or equivalent).For extended storage aliquot contents and freeze at -20℃ or below.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of restoration.Expiration date is one (1) year from date of opening. |
| 背景资料 | AKT is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308.AKT is a cytoplasmic protein also known as AKT1,Protein Kinase B (PKB) and rac (related to A and C kinases).AKT is a key regulator of many signal transduction pathways.AKT Exhibits tight control over cell proliferation and cell viability.Overexpression or inappropriate activation of AKT is noted in many types of cancer.AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors,cytokines and insulin).PI 3-kinase recruits AKT to the membrane,where it is activated by PDK1 phosphorylation.Once phosphorylated,AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.AKT has two main roles:(i) inhibition of apoptosis;(ii) promotion of proliferation.Anti-AKT2 (RAT) PE conjugated Monoclonal Antibody is ideal for investigators involved in Cell Signaling,Cancer,Neuroscience,Signal Transduction research. |
| Uniprot ID | P31751 |
| 基因名全称 | v-akt murine thymoma viral oncogene homolog 2 |
| 推荐稀释比 | ELISA:User Optimized Flow Cytometry:User Optimized Fluorochrome Protein Value:1-2 IHC:User Optimized IF Microscopy:User Optimized WB:User Optimized |
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